On October 26, at 11 am
Speaker: Frédéric Ducancel, Deputy director, Operating management and technological aspects, Department of ImmunoVirology iMETI/DSV/CEA, Fontenay-aux-Roses; Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases, UMR1184, IDMIT Department, Université Paris-Saclay, Inserm, CEA, http://www.idmitcenter.fr
Moderator: Mirian Hayashi, PhD, Associate Professor, Department of Pharmacology, Escola Paulista de Medicina - Unifesp
Pre-clinical animal models are a necessary and legally required step prior to conducting clinical trials. IDMIT (Infectious Diseases, Modeling and Innovative Therapies) is a research department specialized in the development of non-human primate animal models of infections by viruses, bacteria, parasites, but also by toxins that affect humans. These pre-clinical models provide researchers and clinicians with
useful data concerning the physio-pathological parameters that characterize infections, before initiating the various clinical stages that will lead to new vaccines and/or treatments.
After a general presentation of IDMIT's activities, the physio-pathological parameters resulting from the intoxication of macaques by a plant protein toxin will be presented.
These data are currently being used to evaluate the protective efficacy of a polyclonal fraction of equine antibodies against the toxin of interest.
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Speaker further information can be found at: link