List of the current students in the group
João Victor Silva Nani
PUBLICAÇÕES
- Nani JV, Lee RS, Yonamine CM, Sant'Anna OA, Juliano MA, Gadelha A, Mari JJ, Hayashi MAF. (2020) Evaluation of NDEL1 oligopeptidase activity in blood and brain in an animal model of schizophrenia: effects of psychostimulants and antipsychotics. Sci Rep. 2020 Oct 28;10(1):18513. doi: 10.1038/s41598-020-75616-2.
- MAES, M.. NANI, J.V., NOTO, C., RIZZO, L., HAYASHI, M. A. F., BRIETZKE, E. (2020) Impairments in Peripheral Blood T Effector and T Regulatory Lymphocytes in Bipolar Disorder Are Associated with Staging of Illness and Anti-cytomegalovirus IgG Levels. Mol Neurobiol. 2020 Jul 22:pyaa050. doi: 10.1007/s12035-020-02110-1.
- NANI, J. V., DAL MAS, C., YONAMINE, C. M., OTA, V. K., NOTO, C., BELANGERO, S. I., MARI, J. J., BRESSAN, R., CORDEIRO, Q., GADELHA, A., & HAYASHI, M. (2020) A study in first-episode psychosis patients: does angiotensin I-converting enzyme (ACE) activity associated with genotype predict symptoms severity reductions after treatment with the atypical antipsychotic risperidone?. Int J Neuropsychopharmacol. 22, pyaa050. doi: 10.1093/ijnp/pyaa050.
- NANI, J. V., FONSECA, M. C., ENGI, S. A., PERILLO, M. G., DIAS, C. S., GAZARINI, M. L., KORTH, C., CRUZ, F. C., & HAYASHI, M. A. (2020) Decreased nuclear distribution nudE-like 1 enzyme activity in an animal model with dysfunctional disrupted-in-schizophrenia 1 signaling featuring aberrant neurodevelopment and amphetamine-supersensitivity. J Psychopharmacol. (Oxford, England) 34(4), 467-477.
- NANI, J. V., YONAMINE, C. M., CASTRO MUSIAL, D., DAL MAS, C., MARI, J. J., HAYASHI, M. A. F. ACE activity in blood and brain axis in an animal model for schizophrenia: Effects of dopaminergic manipulation with antipsychotics and psychostimulants. World J Biol Psychiatry. 26:1-11. 2019. doi: 10.1080/15622975.2019.1583372.
- MONTE, G. G., NANI, J. V., DE ALMEIDA CAMPOS, M. R., DAL MAS, C., MARINS, L. A. N., MARTINS, L. G., TARSIC, L., MORI, M. A., HAYASHI, M. A. F. Impact of nuclear distribution element genes in the typical and atypical antipsychotics effects on nematode Caenorhabditis elegans: Putative animal model for studying the pathways correlated to schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 92:19-30. 2019. doi: 10.1016/j.pnpbp.2018.12.010.
Lucas de Carvalho Porta
PhD
PROJECT:
Unexpected effects of the covid-19 pandemic: evaluation of possible effects and consequences in mental disorders
PUBLICAÇÕES
- de CARVALHO PORTA, L. C., FADEL, V., CAMPEIRO, J. D., OLIVEIRA, E. B., GODINHO, R. O., & HAYASHI, M. (2020) Biophysical and pharmacological characterization of a full-length synthetic analog of the antitumor polypeptide crotamine. J Mol Med (Berl). 98(11):1561-1571. doi: 10.1007/s00109-020-01975-y.
- PORTA, L. C., CAMPEIRO, J. D., PAPA, G. B., OLIVEIRA, E. B., GODINHO, R. O., RODRIGUES, T., & HAYASHI, M. (2020) In vivo effects of the association of the psychoactive phenotiazine thioridazine on antitumor activity and hind limb paralysis induced by the native polypeptide crotamine. Toxicon 185, 64-71. https://doi.org/10.1016/j.toxicon.2020.06.017
- HAYASHI, M., CAMPEIRO, J. D., PORTA, L. C., SZYCHOWSKI, B., ALVES, W. A., OLIVEIRA, E. B., KERKIS, I., DANIEL, M. C., & KARPEL, R. L. (2020) Crotamine Cell-Penetrating Nanocarriers: Cancer-Targeting and Potential Biotechnological and/or Medical Applications. Methods Mol Biol. (Clifton, N.J.) 2118, 61–89. https://doi.org/10.1007/978-1-0716-0319-2_5
- LIMA, S. C., PORTA, L. C., LIMA, Á. D. C., CAMPEIRO, J. D., MEURER, Y., TEIXEIRA, N. B., DUARTE, T., OLIVEIRA, E. B., PICOLO, G., GODINHO, R. O., SILVA, R. H., HAYASHI, M. A. F. Pharmacological characterization of crotamine effects on mice hind limb paralysis employing both ex vivo and in vivo assays: Insights into the involvement of voltage-gated ion channels in the crotamine action on skeletal muscles. PLoS Negl Trop Dis. 12(8):e0006700. 2018. doi: 10.1371/journal.pntd.0006700.
- CAMPEIRO, J. D., MARINOVIC, M. P., CARAPETO, F. C., DAL MAS, C., MONTE, G. G., PORTA, L. C., NERING, M. B., OLIVEIRA, E. B., HAYASHI, M. A. F. Oral treatment with a rattlesnake native polypeptide crotamine efficiently inhibits the tumor growth with no potential toxicity for the host animal and with suggestive positive effects on animal metabolic profile. Amino Acids. 50(2):267-278. 2018. doi: 10.1007/s00726-017-2513-3.
- HAYASHI, MIRIAN A. F. ; CAMPEIRO, JOANA DARC ; PORTA, LUCAS CARVALHO ; Szychowski, Brian ; Alves, Wendel Andrade ; OLIVEIRA, EDUARDO B. ; Kerkis, Irina ; Daniel, Marie-Christine ; Karpel, Richard L. . Crotamine Cell-Penetrating Nanocarriers: Cancer-Targeting and Potential Biotechnological and/or Medical Applications. Methods in Molecular Biology. 2ed.: Springer US, 2020, p. 61-89.
Joana D'Arc Campeiro
PUBLICAÇÕES
- de CARVALHO PORTA, L. C., FADEL, V., CAMPEIRO, J. D., OLIVEIRA, E. B., GODINHO, R. O., & HAYASHI, M. (2020) Biophysical and pharmacological characterization of a full-length synthetic analog of the antitumor polypeptide crotamine. J Mol Med (Berl). 98(11):1561-1571. doi: 10.1007/s00109-020-01975-y.
- PORTA, L. C., CAMPEIRO, J. D., PAPA, G. B., OLIVEIRA, E. B., GODINHO, R. O., RODRIGUES, T., & HAYASHI, M. (2020) In vivo effects of the association of the psychoactive phenotiazine thioridazine on antitumor activity and hind limb paralysis induced by the native polypeptide crotamine. Toxicon 185, 64-71. https://doi.org/10.1016/j.toxicon.2020.06.017
- HAYASHI, M., CAMPEIRO, J. D., PORTA, L. C., SZYCHOWSKI, B., ALVES, W. A., OLIVEIRA, E. B., KERKIS, I., DANIEL, M. C., & KARPEL, R. L. (2020) Crotamine Cell-Penetrating Nanocarriers: Cancer-Targeting and Potential Biotechnological and/or Medical Applications. Methods Mol Biol. (Clifton, N.J.) 2118, 61–89. https://doi.org/10.1007/978-1-0716-0319-2_5
- CAMPEIRO, J. D., DAM, W., MONTE, G. G., PORTA, L. C., OLIVEIRA, L. C. G., NERING, M. B., VIANA, G. M., CARAPETO, F. C., OLIVEIRA, E. B., van den BORN, J., HAYASHI, M. A. F. Long term safety of targeted internalization of cell penetrating peptide crotamine into renal proximal tubular epithelial cells in vivo. Sci Rep. 9(1):3312. 2019. doi: 10.1038/s41598-019-39842-7.
- LIMA, S. C., PORTA, L. C., LIMA, Á. D. C., CAMPEIRO, J. D., MEURER, Y., TEIXEIRA, N. B., DUARTE, T., OLIVEIRA, E. B., PICOLO, G., GODINHO, R. O., SILVA, R. H., HAYASHI, M. A. F. Pharmacological characterization of crotamine effects on mice hind limb paralysis employing both ex vivo and in vivo assays: Insights into the involvement of voltage-gated ion channels in the crotamine action on skeletal muscles. PLoS Negl Trop Dis. 12(8):e0006700. 2018. doi: 10.1371/journal.pntd.0006700.
- MARINOVIC, M. P., CAMPEIRO, J. D., LIMA, S. C., ROCHA, A. L., NERING, M. B., OLIVEIRA, E. B., MORI, M. A., HAYASHI, M. A. F. Crotamine induces browning of adipose tissue and increases energy expenditure in mice. Sci Rep. 8(1):5057. 2018. doi: 10.1038/s41598-018-22988-1.
- KARPEL, R. L., DA SILVA LIBERATO, M., CAMPEIRO, J. D., BERGEON, L., SZYCHOWSKI, B., BUTLER, A., MARINO, G., CUSIC, J. F., DE OLIVEIRA, L. C. G., OLIVEIRA, E. B., DE FARIAS, M. A., PORTUGAL, R. V., ALVES, W. A., DANIEL, M. C., HAYASHI, M. A. F. Design and characterization of crotamine-functionalized gold nanoparticles. Colloids Surf B Biointerfaces. 163:1-8. 2018. doi: 10.1016/j.colsurfb.2017.12.013.Dal Mas C, Pinheiro DA, Campeiro JD, Mattei B, Oliveira V, Oliveira EB, Miranda A, Perez KR, Hayashi MAF. Biophysical and biological properties of small linear peptides derived from crotamine, a cationic antimicrobial/antitumoral toxin with cell penetrating and cargo delivery abilities. Biochim Biophys Acta Biomembr. 2017 Dec;1859(12):2340-2349. doi: 10.1016/j.bbamem.2017.09.006.
- CAMPEIRO, J. D., MARINOVIC, M. P., CARAPETO, F. C., DAL MAS, C., MONTE, G. G., PORTA, L. C., NERING, M. B., OLIVEIRA, E. B., HAYASHI, M. A. F. Oral treatment with a rattlesnake native polypeptide crotamine efficiently inhibits the tumor growth with no potential toxicity for the host animal and with suggestive positive effects on animal metabolic profile. Amino Acids. 50(2):267-278. 2018. doi: 10.1007/s00726-017-2513-3.
- Marinovic M.P., Dal Mas C., Monte G.G., Felix D., Campeiro J.D., Hayashi M.A.F. (2016) Crotamine: Function Diversity and Potential Applications. In: Gopalakrishnakone P., Inagaki H., Mukherjee A., Rahmy T., Vogel CW. (eds) Snake Venoms. Toxinology. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6648-8_28-1
- CAMPEIRO, J. D., NESHICH, I. P., SANT'ANNA, O. A., LOPES, R., IANZER, D., ASSAKURA, M. T., NESHICH, G., HAYASHI, M. A. F. Identification of snake bradykinin-potentiating peptides (BPPs)-simile sequences in rat brain--Potential BPP-like precursor protein? Biochem Pharmacol. 96(3):202-15. 2015. doi: 10.1016/j.bcp.2015.05.012.
Benjamin Rodríguez Hernandez
MSc
PROJECT:
Analysis of prolyl-oligopeptidase (POP) activity after the treatment with antipsychotics in an animal model for the study of schizophrenia
PUBLICAÇÕES
- RODRÍGUEZ, BENJAMÍN ; NANI, JOÃO VICTOR ; ALMEIDA, PRISCILA G.C. ; BRIETZKE, ELIZA ; LEE, RICHARD S. ; HAYASHI, MIRIAN A.F. . NEUROPEPTIDES AND OLIGOPEPTIDASES IN SCHIZOPHRENIA. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, v. 108, p. 679-693, 2019. https://doi.org/10.1016/j.neubiorev.2019.11.024
Priscila Gasperini Camolesi de Almeida
MSc
PROJECT:
Molecular and cellular study of processes involved in schizophrenia by the biochemical and morphological analysis of neuronal cells
PUBLICAÇÕES
ALMEIDA, PRISCILA G.C.; NANI, JOÃO VICTOR ; OSES, JEAN PIERRE ; BRIETZKE, ELISA ; HAYASHI, MIRIAN A.F. . Neuroinflammation and glial cell activation in mental disorders. Brain, Behavior, & Immunity - Health, v. 2, p. 100034, 2020. https://doi.org/10.1016/j.bbih.2019.100034- RODRÍGUEZ, BENJAMÍN ; NANI, JOÃO VICTOR ; ALMEIDA, PRISCILA G.C. ; BRIETZKE, ELIZA ; LEE, RICHARD S. ; HAYASHI, MIRIAN A.F. . NEUROPEPTIDES AND OLIGOPEPTIDASES IN SCHIZOPHRENIA. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, v. 108, p. 679-693, 2019. https://doi.org/10.1016/j.neubiorev.2019.11.024
- Luana Goes Costa, Iniciação Científica. Título do projeto: Otimização do tratamento antitumoral com a crotamina por associação com a nanopartículas de sílica que permitem a liberação lenta e controlada Lattes
- Daniel Oliveira Pires de Moraes, Iniciação científica, Lattes
